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Old 05-28-2008, 03:48 PM   #1
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C. Diff creating havoc, causing more illnesses and death

Just what I DON'T wanna hear or read: Gut superbug causing more illnesses, deaths - Yahoo! News

ATLANTA - The number of people hospitalized with a dangerous intestinal superbug has been growing by more than 10,000 cases a year, according to a new study.
The germ, resistant to some antibiotics, has become a regular menace in hospitals and nursing homes. The study found it played a role in nearly 300,000 hospitalizations in 2005, more than double the number in 2000.
The infection, Clostridium difficile, is found in the colon and can cause diarrhea and a more serious intestinal condition known as colitis. It is spread by spores in feces. But the spores are difficult to kill with most conventional household cleaners or antibacterial soap.
C-diff, as it's known, has grown resistant to certain antibiotics that work against other colon bacteria. The result: When patients take those antibiotics, competing bacteria die off and C-diff explodes.
This virulent strain of C-diff was rarely seen before 2000.
"The nature of this infection is changing. It's more severe," said Dr. L. Clifford McDonald, a Centers for Disease Control and Prevention expert who was not part of the study.
There are other factors that play into the rise of C-diff cases as well, including a larger of number of patients who are older and sicker. "And there may be some overuse and inappropriate use of antibiotics," said Dr. Marya Zilberberg, a University of Massachusetts researcher and lead author of the study.
The Zilberberg study was based on a sample of more than 36 million annual discharges from non-governmental U.S. hospitals. That data was used to generate the study's national estimates.
The research is being published in the June issue of Emerging Infectious Diseases, a CDC publication.
Using other scientists' estimates, the study concluded that 2.3 percent of the cases in 2004 were fatal — about 5,500 deaths. That was nearly double the percentage of C-diff-related cases that ended in death in 2000.
Many of the people who died had other health problems. The study did not try to determine if Clostridium difficile was the main cause of death in each case, Zilberberg said.
But earlier research concluded the infection is the underlying cause of thousands of deaths annually, and the problem is getting worse.
C-diff has become an acute health concern in Canada, where it was blamed for 260 deaths at seven Ontario hospitals recently, and 2,000 deaths in Quebec since 2002.
The Association for Professionals in Infection Control and Epidemiology is currently working with U.S. hospitals to study prevalence of the infection and what infection control measures seem to work best.
"This is not a time for alarm, but more a time for educating health professionals to understand this particular pathogen," said Kathy Warye, chief executive of the Washington, D.C.-based association.

Any thoughts or comments on the subject???
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Old 08-18-2008, 01:59 AM   #2
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Re: C. Diff creating havoc, causing more illnesses and death

So far, in the months of July and August, I've seen two patients whose end-stage diagnoses have resulted from rampant and uncontrollable systemic C-Diff infections. As a hospice nurse, I found that rather surprising as I'm used to C-Diff resulting in lingering diarrhea and little else. These patients had apparently suffered colon breaches resulting in peritonitis and ultimately multi-organ failure. Of course, co-morbidities were present.

The more shocking issue here is that these people are remanded into home-care settings without first receiving any education regarding appropriate protective equipment or even knowledge of possible communicability. One family was washing their dying C-Diff infected family member's soiled bed-linens with the family laundry (which included clothing for a four-year-old)!

Of course, the old handwashing and gloving / gowning argument is salient here, but I feel that we need to do a LOT more education in order to slow the spread of these newer and more virulent pathogens.

Jus' Sayin'

-J
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